CTRI Clinical Trial Report

Comprehensive clinical evaluation of safety and efficacy for our skincare formulations registered under the Clinical Trials Registry of India.

• Objective: Evaluate in-vivo dermatological safety and efficacy of the product for outcomes such as reduction in wrinkles, improvement in skin brightness, hydration, elasticity and even-tone (specific endpoints vary by product).

• Population: 36 healthy volunteers (approx. 26 female / 10 male).

• Age Range:
  Anti-ageing products – 35 – 55 years.
  Brightening / pigment products – 18 – 40 years.

• Design: Double-blind, non-comparative; subjects served as their own control.

• Duration:
  Anti-ageing trials – 42 days after first application.
  
  Brightening trials – 28 days after first application.

• Subject Selection:
  Inclusion: healthy volunteers with target skin concerns (e.g., crow’s feet wrinkles, dry skin, or visible post-inflammatory hyperpigmentation ≥ 3 mm).
  
  Exclusion: known allergies, relevant medical conditions, conflicting treatments.
  

• Randomisation & Blinding: Double-blind; each subject acted as own reference.
  
• Procedures & Assessments:
  
  Subject Self-Evaluation questionnaires.
  
  Dermatological Evaluation – cosmetic acceptability & efficacy.
  
  Instrumental tests depending on product:
  
  Chromametry / Mexametry – measure pigmentation & redness.
  
  Corneometry – skin hydration.
  
  Cutometry – elasticity / firmness.
  
  Tewametry – water-loss barrier.
  
  Digital Photographs at each visit.
  

Examination Schedule

Typical visit pattern:

• Screening & T0 – registration, consent, baseline photography.
  
• T+14 Days (or T+7 for 28-day studies) – interim assessments.
  
• T+28 Days – mid or final (for 28-day studies).
  
• T+42 Days – final (for 42-day studies).