Bio Code Tranexamic Acid & Vitamin C Face Wash

Our AI-Enhanced Formulation leverages advanced AI technology to optimize ingredient combinations, ensuring maximum efficacy, stability, and targeted results. Clinically tested and dermatologist recommended, this face wash is your gateway to brighter, more radiant skin.

1. Tranexamic Acid (2%):

Function: Inhibits melanin transfer to reduce pigmentation and dark spots.

Key Benefits:

• Brightens skin tone and reduces hyperpigmentation.
• Inhibits tyrosinase activity, preventing dark spots from forming.
• Evens skin tone and minimizes post-inflammatory hyperpigmentation.

Clinical Evidence: Demonstrates significant reduction in pigmentation and melasma after 8 weeks of use.

2. Stable Vitamin C (3-O-Ethyl Ascorbic Acid) (2%):

Function: Powerful antioxidant that brightens skin and protects against environmental damage.

Key Benefits:

• Brightens and evens out skin tone.
• Boosts collagen production for improved firmness.
• Protects against free radical damage caused by UV exposure.

Clinical Evidence: Proven stability and efficacy in reducing hyperpigmentation and enhancing brightness.

3. Niacinamide (Vitamin B3) (1%):

Function: Multi-functional active that reduces redness, brightens, and strengthens the skin barrier.

Key Benefits:

• Reduces redness and irritation.
• Evens out skin tone by inhibiting melanin transfer.
• Enhances the skin barrier, preventing moisture loss.

Clinical Evidence: Significantly reduces hyperpigmentation and improves overall skin tone within 4 weeks.

Skincare Routine Recommendation:

• Step 1: Cleanser (Tranexamic Acid & Vitamin C)
• Step 2: Serum (Tranexamic Acid & Vitamin C)
• Step 3: Moisturizer (Niacinamide & Hyaluronic Acid)

Tranexamic Acid & Vitamin C Face Wash — Protocol Summary

1. Study Identity
• CTRI Registration No.: CTRI/2025/07/090241
• Type: Interventional, single-arm, cosmeticeutical study
• Sponsor: Bio Veda Farmacy Pvt. Ltd. (India)
• Study Site: Conducted at an approved dermatology research facility in Mumbai, India

2. Objective
Evaluate the in-vivo safety and efficacy of a skincare formulation containing Tranexamic Acid & Vitamin C in terms of
reduction in hyper-pigmentation (Acne PIH), improvement in skin even tone and brightness.

3. Study Design
Parameter Details
Design - Single arm, interventional
Blinding - Participant & Outcome Assessor blinded
Sample Size - 36 subjects (26 female, 10 male)
Population - Healthy men & women, 18–40 yrs, with normal skin and visible Acne PIH ≥3 mm
Duration - 28 days (twice-daily application)
Comparator - None (no placebo arm)

4. Intervention Details
• Product: Tranexamic Acid & Vitamin C Face Wash
• Application: Apply on whole face twice daily for 28 days
5. Inclusion & Exclusion
• Inclusion: Healthy men & women (18–40 yrs) with normal skin and at least one visible Acne PIH spot ≥3 mm.
• Exclusion: Pregnancy, breastfeeding, chronic dermatoses, uncontrolled diabetes/asthma/thyroid disorders, recent
surgery, hypersensitivity, systemic corticosteroid/anti-inflammatory use.
6. Outcomes & Evaluation
• Primary: Reduction in hyper-pigmentation (Acne PIH), improvement in even tone & skin brightness.
• Assessments: Subject self-evaluation, dermatological evaluation (cosmetic acceptability & efficacy), chromametry,
mexametry, and digital photographs at Baseline, Day 14 & Day 28.
7. Safety & Regulatory
• Ethics: Approved by an Institutional Ethics Committee (Mumbai).
• DCGI: Not required / Not applicable.
• Monitoring: Adverse events monitored during study.
8. Practical Takeaways
✓ Dermatologically tested on Indian volunteers.
✓ Clinically proven endpoints: pigmentation reduction, brighter and even-toned skin.
✓ Evidence-based actives: Tranexamic Acid + Vitamin C.
✓ Visible tone and brightness improvement in 28 days.
✓ Reviewed & approved by independent ethics committee