Bio Code Alpha Arbutin & Licorice Extract Brightening Moisturizer

Our AI-Enhanced Formulation is designed using advanced AI technology to optimize ingredient synergy, ensuring every component works together for maximum results. The formula is clinically tested and dermatologist recommended, targeting concerns like pigmentation, uneven skin tone, and dullness while keeping your skin hydrated and protected.

Key Ingredients Explained:

• 1.5% Alpha Arbutin
  A powerful skin-brightening ingredient that helps reduce the appearance of pigmentation, dark spots, and uneven skin tone. It works by slowing down melanin production, leaving your skin looking clearer and more radiant.
  
• 1% Licorice Extract (Glabridin)
  Known for its natural skin-brightening and soothing properties. It helps minimize redness, blotchiness, and discoloration, while providing a calming effect on sensitive skin.
  
• 2% Niacinamide (Vitamin B3)
  A multi-tasking hero ingredient that improves overall skin health. It works to brighten dullness, reduce redness, refine pores, and strengthen the skin barrier against environmental stressors.
  
• 0.5% Vitamin E (Tocopherol)
  A powerful antioxidant that shields the skin from free radicals and environmental damage. It also nourishes and keeps the skin soft, supple, and healthy.
  
• 1% Tranexamic Acid
  Highly effective in addressing stubborn pigmentation and dark spots. It helps regulate melanin production and prevents new discoloration from forming, making skin tone more even over time.
  
• 1.5% Multi-Molecular Hyaluronic Acid
  Provides deep hydration at multiple layers of the skin, locking in moisture for long-lasting plumpness and radiance. This helps improve elasticity and smoothness.
  
• 0.3% Allantoin
  A soothing agent that helps calm irritation, reduce sensitivity, and promote skin healing. Perfect for keeping skin balanced and comfortable.
  

Together, these ingredients create a balanced, effective, and gentle formulation that targets pigmentation and uneven tone while ensuring your skin stays hydrated, soothed, and protected every day.

Skincare Routine Recommendation:

• Step 1: Cleanser (Brightening & Even Tone)

• Step 2: Serum (Advanced Brightening Serum)

• Step 3: Moisturizer (Alpha Arbutin & Licorice Extract)

Alpha Arbutin & Licorice Moisturizer — Protocol Summary

1. Study Identity
• CTRI Registration No.: CTRI/2025/06/089881
• Type: Interventional, single-arm, cosmeticeutical study
• Sponsor: Bio Veda Farmacy Pvt. Ltd. (India)
• Study Site: Conducted at an approved dermatology research facility in Mumbai, India

2. Objective
Evaluate the in-vivo dermatological safety and efficacy of a skincare formulation containing Alpha Arbutin & Licorice
Extract for reduction in dark spots, improvement in brightness, even tone and skin luminosity.

3. Study Design
Parameter Details
Design - Single arm, interventional
Blinding - Participant & Outcome Assessor blinded
Sample Size - 36 subjects (26 female, 10 male)
Population - Healthy men & women, 18–40 yrs, acne pigmentary spots ≥3 mm
Duration - 28 days (twice-daily application)
Comparator - None (no placebo arm)

4. Intervention Details
• Product: Alpha Arbutin & Licorice Extract Moisturizer
• Application: Apply on whole face twice daily for 28 days

5. Inclusion & Exclusion
• Inclusion: Healthy men & women (18–40 yrs) with acne pigmentary spots ≥3 mm.
• Exclusion: Pregnancy, breastfeeding, chronic dermatoses, uncontrolled diabetes/asthma/thyroid disorders, recent
surgery, hypersensitivity, systemic corticosteroid/anti-inflammatory use.

6. Outcomes & Evaluation
• Primary: Reduction in dark spots, improvement in brightness, even tone & luminosity. • Assessments: Subject
self-evaluation, dermatological evaluation, chromametry, mexametry, expert assessment, and digital photographs at
Baseline, 30 min, Day 7 & Day 28.

7. Safety & Regulatory
• Ethics: Approved by an Institutional Ethics Committee (Mumbai).
• DCGI: Not required / Not applicable.
• Monitoring: Adverse events monitored during study.

8. Practical Takeaways
✓ Dermatologically tested on Indian volunteers.
✓ Clinically proven endpoints: dark spot reduction, brightness, even tone & luminosity.
✓ Evidence-based actives: Alpha Arbutin + Licorice Extract.
✓ Visible results in 28 days.
✓ Reviewed & approved by independent ethics committee.